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Glycine is the simplest amino acid. Produced naturally by the body and supplied by the diet, it is particularly abundant in collagen, where it accounts for around one third of the amino acids.

Discover the role of glycine, its dietary sources, the difference between glycine and L-glycine, and our selection of food supplements containing this active ingredient.

Glycine: role, sources and L-glycine | NATURAMedicatrix

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L-Glycine

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Active ingredients guide

Glycine: the smallest amino acid, found throughout the body

Glycine is a so-called “non-essential” amino acid: the body is able to make it itself, in particular from another amino acid, serine. It is also supplied every day by the diet.

Unlike citrulline, glycine is a proteinogenic amino acid: it is directly incorporated into proteins. It is also the smallest molecule in this family, which gives it a special place in the structure of certain proteins, such as collagen.

Non-essential amino acid

The body produces glycine and also obtains it from the diet.

A cornerstone of collagen

Roughly one in three amino acids in collagen is glycine.

A naturally sweet taste

Its name comes from the Greek glykys, “sweet”, a reference to its slightly sweet flavour.

How it works

What is the role of glycine in the body?

Glycine is involved in many processes. It is used to build proteins, as well as several other molecules produced naturally by the body.

Glycine and collagen

Collagen is the most abundant protein in the body: it is found in the skin, bones, tendons and cartilage. Its structure is based on a repeating sequence of three amino acids in which glycine occurs at every third position. Its small size allows collagen chains to wind tightly into a triple helix.

A building block for other molecules

Glycine contributes to the synthesis of several molecules naturally present in the body:

Glutathione

Made up of three amino acids: glutamate, cysteine and glycine.

Creatine

Produced by the body from glycine, arginine and methionine.

Bile salts

Some of the bile acids produced by the liver are conjugated with glycine.

Haem

Glycine is one of the starting points of its synthesis. Haem is the iron-containing part of haemoglobin.

A messenger in the nervous system

Glycine also acts as a neurotransmitter, particularly in the spinal cord and the brainstem. This role explains the interest it attracts from scientific research.

These points describe physiological mechanisms. They do not mean that supplementation systematically produces any particular effect.

Nutrition

Where is glycine found naturally?

Foods rich in collagen are the most concentrated sources of glycine: gelatine, bone broths, and the skin and cartilage of meat and fish.

It is also found, in smaller amounts, in meat, fish, eggs, dairy products and pulses. Dietary intake adds to the body's own natural production.

What the research says

Why is glycine discussed in relation to sleep?

Glycine is the subject of scientific research on sleep, owing to its role in the nervous system and in the regulation of body temperature. The available studies involve small groups of participants, with varying protocols.

No health claim relating to glycine is currently authorised in the European Union. This research therefore cannot guarantee any particular effect from a glycine-based food supplement.

Understanding formulations

Glycine, L-glycine or bisglycinate: what is the difference?

Glycine and L-glycine

Glycine is the only proteinogenic amino acid that has no “L” or “D” form. The terms “glycine” and “L-glycine” therefore refer to the same molecule. The name “L-glycine” is mainly used by analogy with the other amino acids.

Pure glycine

A pure glycine powder contains only this amino acid. The amount stated on the label corresponds directly to the glycine supplied.

Bisglycinates

In a bisglycinate, such as magnesium bisglycinate, a mineral is bound to two glycine molecules. Here, glycine acts as a ligand for the mineral rather than as the main ingredient of the formula.

Buying guide

How to choose a glycine supplement?

Purity

Check whether the product contains glycine on its own or combined with other ingredients.

Amount per serving

Read the label to find out the amount supplied and the daily dose recommended by the manufacturer.

The ingredient list

A simple formula, free from additives and sweeteners, lets you know exactly what you are consuming.

The format

In powder form, glycine dissolves easily in water, and its naturally sweet taste makes it pleasant to take.

Our selection

Pure L-Glycine powder — 300 g

NATURAMedicatrix offers a 100% pure glycine powder, free from additives, with a naturally sweet taste. Its 300 g format, with 2.5 g per serving, makes it easy to adjust the amount according to the directions for use on the label.

Discover our L-Glycine 300 g →

Frequently asked questions

Glycine FAQ

What is glycine?

Glycine is the simplest amino acid. It is produced naturally by the body, supplied by the diet and incorporated into proteins, collagen in particular.

What is the difference between glycine and L-glycine?

None: they are the same molecule. Glycine has no “L” and “D” enantiomers.

What is the link between glycine and collagen?

Glycine makes up roughly one third of the amino acids in collagen. Its small size is essential to the triple helix structure of this protein.

Which foods contain glycine?

Mainly foods rich in collagen: gelatine, bone broths, skin and cartilage. Meat, fish, eggs and pulses also contain it.

Does glycine really taste sweet?

Yes. In fact, its name comes from the Greek glykys, meaning “sweet”. Its flavour is slightly sweet, although it is not a sugar.

Does magnesium bisglycinate provide glycine?

Bisglycinate does contain glycine, bound to the mineral. However, the amounts remain small compared with a pure glycine powder, in which it is the only ingredient.

Is glycine suitable for vegetarians?

That depends on its origin. The glycine used in food supplements is generally obtained by synthesis or fermentation, rather than extracted from animal products. Check the manufacturer's information on the label or product page.

What precautions should be taken before supplementation?

Follow the directions on the label. If you are pregnant or breastfeeding, have a medical condition or are taking medication, seek advice from a healthcare professional before using a supplement containing glycine.

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Luxembourg
Call us: +3242900070
Fax: +324 341 29 21
Email us:

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Prendre soin de soi. C’est déjà agir.

Glycine

L-Glycine

Magnesium Bisglycinate

Cocoa Keto (collagen peptides)

Glycine: the smallest amino acid, found throughout the body

What is the role of glycine in the body?

Glycine and collagen

A building block for other molecules

Glutathione

Creatine

Bile salts

Haem

A messenger in the nervous system

Where is glycine found naturally?

Why is glycine discussed in relation to sleep?

Glycine, L-glycine or bisglycinate: what is the difference?

Glycine and L-glycine

Pure glycine

Bisglycinates

How to choose a glycine supplement?

Purity

Amount per serving

The ingredient list

The format

Pure L-Glycine powder — 300 g

Glycine FAQ

What is glycine?

What is the difference between glycine and L-glycine?

What is the link between glycine and collagen?

Which foods contain glycine?

Does glycine really taste sweet?

Does magnesium bisglycinate provide glycine?

Is glycine suitable for vegetarians?

What precautions should be taken before supplementation?

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