Digestive enzymes: protease, lipase, DPP-IV

Octobre Rose

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Digestive enzymes are proteins that break food down into smaller components: proteases for proteins, lipases for fats, amylases for carbohydrates, lactase for lactose… Food supplements often combine several of them, of plant, fungal or microbial origin.

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NATURAMedicatrix

SIBO Digest

60 capsules

€32.18 €34.50

Pack

NATURAMedicatrix

SIBO Pack

2 x 60 capsules

€50.00

Inulac 30 lozenges | Digestion, Transit & Gut Flora

-20%

SoriaBel

Inulac

30 tablets

€13.15 €16.45

Out of stock

NATURAMedicatrix

Gluzym (digestive enzymes)

60 capsules

€36.50

Active ingredients guide

Digestive enzymes: role, types and supplements

Digestive enzymes are proteins that break the large molecules in food down into components small enough to be absorbed by the intestine. Each one is specialised: an enzyme that cuts proteins does not act on fats, and vice versa.

The body makes them itself, in the saliva, the stomach, the pancreas and the wall of the small intestine. The enzymes in food supplements, on the other hand, are most often obtained by fermentation of microscopic fungi or extracted from fruit, such as papain from papaya.

Proteins

That speed up a specific chemical reaction without being used up.

One target each

Proteins, fats, starch, lactose, fibre: each nutrient has its own enzyme.

Activity units

Their dosage is expressed in units (DU, HUT, ALU, FIP…) rather than in milligrams.

Role

What are the main digestive enzymes?

They are classified according to the type of nutrient they break down:

Proteases

They cut proteins into peptides and then into amino acids. Pepsin acts in the stomach; trypsin and chymotrypsin come from the pancreas.

Lipases

They break fats (triglycerides) down into fatty acids and smaller glycerides. The main one is produced by the pancreas.

Amylases

They break starch down into simpler sugars. The work begins in the mouth, with salivary amylase.

Lactase and cellulase

Lactase splits the lactose in milk into glucose and galactose. Cellulase, which humans do not produce, acts on the cellulose in plants.

Origin

Where do the enzymes in supplements come from?

Most are produced by fermentation of micro-organisms, notably fungi of the genus Aspergillus. Some are of plant origin: papain is extracted from papaya latex, bromelain from pineapple.

Formulas often combine several enzymes in a single complex, sometimes with plants, fibre or lactic ferments. Some contain enzymes capable of cutting proline-rich bonds, which are very common in gluten proteins: this is the case of prolyl oligopeptidase.

What research says

Digestive enzyme supplements: what does the science say?

Researchers are particularly interested in how stable enzymes are in the face of stomach acidity and in their actual activity in the digestive tract, especially for enzymes that break down gluten proteins.

To date, no health claim relating to the enzymes contained in these products is authorised in the European Union. This research therefore does not allow any particular effect to be attributed to a food supplement containing them.

Buying guide

How to choose a digestive enzyme supplement?

The enzymes included

A broad-spectrum formula combines protease, lipase, amylase and lactase.

The stated activity

Choose a label that shows the activity units of each enzyme, not just the weight of the complex.

The origin

Fermentation or fruit: the origin of the enzymes is useful to know, particularly for a plant-based diet.

When to take them

These products are generally taken at mealtimes: follow the directions for use.

Our selection

Our digestive enzyme supplements

Gluzym — 60 capsules

The ZyMate® complex (α-amylase, protease, lactase, cellulase, lipase, 750 mg) and 300 mg of Tolerase® G prolyl oligopeptidase per 3 capsules.

Discover Gluzym →

SIBO Digest — 60 capsules

The DigeZyme® enzyme complex (150 mg per 3 capsules) combined with turmeric, gentian and fennel.

Discover SIBO Digest →

Inulac — 30 tablets

Papain and amylase, with inulin, pineapple and three strains of lactic ferments.

Discover Inulac →

SIBO Pack — 2 x 60 capsules

SIBO Digest and LF-Gingembre together in one pack.

Discover the SIBO Pack →

Frequently asked questions

Digestive enzymes FAQ

What is a digestive enzyme?

A protein that breaks a specific food molecule (protein, fat, starch, lactose…) down into smaller components. The body naturally produces them all along the digestive tract.

Which foods contain digestive enzymes?

Some raw fruits naturally contain them: papaya (papain), pineapple (bromelain) or kiwi fruit (actinidin). Cooking destroys most of them.

What is the difference between DPP-IV and prolyl oligopeptidase?

They are two enzymes that cut bonds involving proline. DPP-IV detaches two-amino-acid fragments from the end of a protein; prolyl oligopeptidase cuts within the chain.

Where can you buy digestive enzymes?

In pharmacies, organic shops and online. At NATURAMedicatrix, we offer several formulas, from Gluzym to SIBO Digest. Do not exceed the stated dose and, during pregnancy and breastfeeding, ask your doctor for advice.

Nos actifs incontournables

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NATURAMedicatrix × Elsee

Your supplements reimbursed Up to 70%

NATURAMedicatrix is an Elsee partner. Order your supplements on naturamedicatrix.fr, send your invoice to Elsee and benefit from the reimbursement provided by your coverage.

Further information

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from €35 at a pickup point*

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order placed before 11:45 AM

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by phone or by appointment

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NATURAMedicatrix
8, Hannert dem Duarref
9772 Troine (Wincrange)
Luxembourg
Call us: +3242900070
Fax: +324 341 29 21
Email us:

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Your account

Store information

NATURAMedicatrix
8, Hannert dem Duarref
9772 Troine (Wincrange)
Luxembourg
Call us: +3242900070
Fax: +324 341 29 21
Email us:

Delivery offered

Your automatic discounts

Payment in 2 or 3 instalments

Up to 70% reimbursed

Prendre soin de soi. C’est déjà agir.

Digestive enzymes

SIBO Digest

SIBO Pack

Inulac

Gluzym (digestive enzymes)

Digestive enzymes: role, types and supplements

What are the main digestive enzymes?

Proteases

Lipases

Amylases

Lactase and cellulase

Where do the enzymes in supplements come from?

Digestive enzyme supplements: what does the science say?

How to choose a digestive enzyme supplement?

The enzymes included

The stated activity

The origin

When to take them

Our digestive enzyme supplements

Gluzym — 60 capsules

SIBO Digest — 60 capsules

Inulac — 30 tablets

SIBO Pack — 2 x 60 capsules

Digestive enzymes FAQ

What is a digestive enzyme?

Which foods contain digestive enzymes?

What is the difference between DPP-IV and prolyl oligopeptidase?

Where can you buy digestive enzymes?

Nos actifs incontournables